A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer

Disrupted regulation of cellular processes is considered one of the hallmarks of cancer. We analyze metabolomic and transcriptomic profiles jointly collected from breast cancer and hepatocellular carcinoma patients to explore the associations between the expression of metabolic enzymes and the level...

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Main Authors: Noam Auslander, Keren Yizhak, Adam Weinstock, Anuradha Budhu, Wei Tang, Xin Wei Wang, Stefan Ambs, Eytan Ruppin
格式: Artigo
语言:英语
出版: 2016
在线阅读:https://doi.org/10.1038/srep29662
https://www.nature.com/articles/srep29662.pdf
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