Three-Dimensional Study of Alzheimer’s Disease Hallmarks Using the iDISCO Clearing Method

Amyloidosis is a major problem in over one hundred diseases, including Alzheimer's disease (AD). Using the iDISCO visualization method involving targeted molecular labeling, tissue clearing, and light-sheet microscopy, we studied plaque formation in the intact AD mouse brain at up to 27 months...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Thomas Liebmann, Nicolas Renier, Karima Bettayeb, Paul Greengard, Marc Tessier‐Lavigne, Marc Flajolet
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2016
Rochtain ar líne:https://doi.org/10.1016/j.celrep.2016.06.060
https://www.cell.com/article/S2211124716308142/pdf
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