Mesenchymal stem cells alleviate experimental rheumatoid arthritis through microRNA-regulated IκB expression

Abstract Previous studies have demonstrated that mesenchymal stem cell (MSC) transplantation reduces the severity of collagen-induced arthritis (CIA) in mice, which is a model for rheumatoid arthritis (RA) in humans. However, the underlying molecular mechanisms remain ill-defined. Here, we showed th...

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Auteurs principaux: Xin Yan, Yurong Cen, Qin Wang
Format: Artigo
Langue:anglais
Publié: 2016
Accès en ligne:https://doi.org/10.1038/srep28915
https://www.nature.com/articles/srep28915.pdf
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