Autoantibodies against thrombospondin type 1 domain–containing 7A induce membranous nephropathy

Autoantibodies against thrombospondin type 1 domain–containing 7A induce membranous nephropathy

Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults, and one-third of patients develop end-stage renal disease (ESRD). Circulating autoantibodies against the podocyte surface antigens phospholipase A2 receptor 1 (PLA2R1) and the recently identified thrombospondin typ...

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Main Authors: Nicola M. Tomas, Elion Hoxha, Anna T. Reinicke, Lars Fester, Udo Helmchen, Jens Gerth, Friederike Bachmann, Klemens Budde, Friedrich Koch‐Nolte, Gunther Zahner, Gabriele M. Rune, Gérard Lambeau, Catherine Meyer-Schwesinger, Rolf A.K. Stahl
Format: Artigo
Language:English
Published: 2016
Online Access:https://doi.org/10.1172/jci85265
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https://doi.org/10.1172/jci85265

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