Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway
In chemotaxing ameboid cells, a complex leading-edge signaling circuit forms on the cytoplasmic leaflet of the plasma membrane and directs both actin and membrane remodeling to propel the leading edge up an attractant gradient. This leading-edge circuit includes a putative amplification module in wh...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | angleščina |
Izdano: |
2016
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Online dostop: | https://doi.org/10.1016/j.bpj.2016.03.001 |
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