Covalent DNA–Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells
N,N-Bis-(2-chloroethyl)-phosphorodiamidic acid (phosphoramide mustard, PM) and N,N-bis-(2-chloroethyl)-amine (nornitrogen mustard, NOR) are the two biologically active metabolites of cyclophosphamide, a DNA alkylating drug commonly used to treat lymphomas, breast cancer, certain brain cancers, and a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2015
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| Online Access: | https://doi.org/10.1021/acs.chemrestox.5b00430 |
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