Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis

Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus responsible for the development of adult T-cell leukemia (ATL). Although HTLV-1 harbors an oncogene, tax, that transforms T cells in vitro and induces leukemia in transgenic mice, tax expression is frequently disrupted in ATL, ma...

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Main Authors: Guangyong Ma, Jun‐ichirou Yasunaga, Masao Matsuoka
格式: Revisão
語言:英语
出版: 2016
在線閱讀:https://doi.org/10.1186/s12977-016-0249-x
https://retrovirology.biomedcentral.com/track/pdf/10.1186/s12977-016-0249-x
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