Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

OBJECTIVES: To investigate, using a Mendelian randomisation approach, whether heavier smoking is associated with a range of regional adiposity phenotypes, in particular those related to abdominal adiposity. DESIGN: Mendelian randomisation meta-analyses using a genetic variant (rs16969968/rs1051730 i...

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Auteurs principaux:	Richard Morris, Amy E. Taylor, Meg Fluharty, Johan Hå‌kon Bjø‌rngaard, Bjørn Olav Åsvold, Maiken E. Gabrielsen, Archie Campbell, Riccardo E. Marioni, Meena Kumari, Tellervo Korhonen, Satu Männistö, Pedro Marques‐Vidal, Marika Kaakinen, Alana Cavadino, Iris Postmus, Lise Lotte N. Husemoen, Tea Skaaby, Tarun Ahluwalia, Jorien L. Treur, Gonneke Willemsen, Caroline Dale, S. Goya Wannamethee, Jari Lahti, Aarno Palotie, Katri Räikkönen, Alex McConnachie, Sandosh Padmanabhan, Andrew Wong, Christine Dalgård, Lavinia Paternoster, Yoav Ben‐Shlomo, Jessica Tyrrell, L. John Horwood, David M. Fergusson, Martin A. Kennedy, Ellen A. Nøhr, Lene Christiansen, Kirsten Ohm Kyvik, Diana Kuh, Graham Watt, Johan G. Eriksson, Peter H. Whincup, Jacqueline M. Vink, Dorret I. Boomsma, George Davey Smith, Debbie A. Lawlor, Allan Linneberg, Ian Ford, J. Wouter Jukema, Chris Power, Elina Hyppönen, Marjo‐Riitta Järvelin, Martin Preisig, Katja Borodulin, Jaakko Kaprio, Mika Kivimäki, Blair H. Smith, Caroline Hayward, Pål Romundstad, Thorkild I. A. Sørensen, Marcus R. Munafò, Naveed Sattar
Format:	Revisão
Langue:	anglais
Publié:	2015
Accès en ligne:	https://doi.org/10.1136/bmjopen-2015-008808 https://bmjopen.bmj.com/content/bmjopen/5/8/e008808.full.pdf
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Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

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