Topologically associated domains enriched for lineage-specific genes reveal expression-dependent nuclear topologies during myogenesis
The linear distribution of genes across chromosomes and the spatial localization of genes within the nucleus are related to their transcriptional regulation. The mechanistic consequences of linear gene order, and how it may relate to the functional output of genome organization, remain to be fully r...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Acesso em linha: | https://doi.org/10.1073/pnas.1521826113 https://www.pnas.org/content/pnas/113/12/E1691.full.pdf |
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