Topologically associated domains enriched for lineage-specific genes reveal expression-dependent nuclear topologies during myogenesis

The linear distribution of genes across chromosomes and the spatial localization of genes within the nucleus are related to their transcriptional regulation. The mechanistic consequences of linear gene order, and how it may relate to the functional output of genome organization, remain to be fully r...

詳細記述

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書誌詳細
主要な著者: Daniel Neems, Arturo G. Garza-Gongora, Erica D. Smith, Steven T. Kosak
フォーマット: Artigo
言語:英語
出版事項: 2016
オンライン・アクセス:https://doi.org/10.1073/pnas.1521826113
https://www.pnas.org/content/pnas/113/12/E1691.full.pdf
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