Topologically associated domains enriched for lineage-specific genes reveal expression-dependent nuclear topologies during myogenesis

The linear distribution of genes across chromosomes and the spatial localization of genes within the nucleus are related to their transcriptional regulation. The mechanistic consequences of linear gene order, and how it may relate to the functional output of genome organization, remain to be fully r...

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Hlavní autoři: Daniel Neems, Arturo G. Garza-Gongora, Erica D. Smith, Steven T. Kosak
Médium: Artigo
Jazyk:angličtina
Vydáno: 2016
On-line přístup:https://doi.org/10.1073/pnas.1521826113
https://www.pnas.org/content/pnas/113/12/E1691.full.pdf
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