An ankylosing spondylitis-associated genetic variant in the<i>IL23R-IL12RB2</i>intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation
To explore the functional basis for the association between ankylosing spondylitis (AS) and single-nucleotide polymorphisms (SNPs) in the IL23R-IL12RB2 intergenic region. We performed conditional analysis on genetic association data and used epigenetic data on chromatin remodelling and transcription...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2016
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| On-line přístup: | https://doi.org/10.1136/annrheumdis-2015-208640 https://ard.bmj.com/content/annrheumdis/75/12/2150.full.pdf |
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