The effects of sample size on population genomic analyses – implications for the tests of neutrality
One of the fundamental measures of molecular genetic variation is the Watterson's estimator (θ), which is based on the number of segregating sites. The estimation of θ is unbiased only under neutrality and constant population growth. It is well known that the estimation of θ is biased when thes...
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格式: | Artigo |
语言: | 英语 |
出版: |
2016
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在线阅读: | https://doi.org/10.1186/s12864-016-2441-8 https://bmcgenomics.biomedcentral.com/track/pdf/10.1186/s12864-016-2441-8 |
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