Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic Strategies

Survivin is the smallest member of the inhibitor of apoptosis protein family, which has key roles in regulating cell division and inhibiting apoptosis by blocking caspase activation.Survivin is highly expressed in most human cancers, such as lung, pancreatic and breast cancers, relative to normal ti...

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Main Authors: Xun Chen, Ning Duan, Caiguo Zhang, Wentao Zhang
格式: Revisão
語言:英语
出版: 2016
在線閱讀:https://doi.org/10.7150/jca.13332
https://www.jcancer.org/v07p0314.pdf
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