Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition

With bacterial resistance becoming a serious threat to global public health, antimicrobial peptides (AMPs) have become a promising area of focus in antibiotic research. AMPs are derived from a diverse range of species, from prokaryotes to humans, with a mechanism of action that often involves disrup...

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Hlavní autoři: Matthieu G. Gagnon, Raktim N. Roy, Ivan B. Lomakin, Tanja Florin, Alexander S. Mankin, Thomas A. Steitz
Médium: Artigo
Jazyk:angličtina
Vydáno: 2016
On-line přístup:https://doi.org/10.1093/nar/gkw018
https://academic.oup.com/nar/article-pdf/44/5/2439/17438220/gkw018.pdf
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