Long noncoding RNA <i>UPAT</i> promotes colon tumorigenesis by inhibiting degradation of UHRF1

Long noncoding RNA <i>UPAT</i> promotes colon tumorigenesis by inhibiting degradation of UHRF1

Significance Many long noncoding RNAs (lncRNAs) play critical roles in tumor development. Here we show that an lncRNA termed UPAT [ubiquitin-like plant homeodomain and really interesting new gene finger domain-containing protein 1 (UHRF1) Protein Associated Transcript] is required for the tumorigeni...

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Bibliographic Details
Main Authors: Kenzui Taniue, Akiko Kurimoto, Hironobu Sugimasa, Emiko Nasu, Yasuko Takeda, Kei Iwasaki, Takeshi Nagashima, Mariko Okada, Masaaki Oyama, Hiroko Kozuka‐Hata, Masaya Hiyoshi, Joji Kitayama, Lumi Negishi, Yoshihiro Kawasaki, Tetsu Akiyama
Format: Artigo
Language:English
Published: 2016
Online Access:https://doi.org/10.1073/pnas.1500992113
https://www.pnas.org/content/pnas/113/5/1273.full.pdf
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