KMAD: knowledge-based multiple sequence alignment for intrinsically disordered proteins

Intrinsically disordered proteins (IDPs) lack tertiary structure and thus differ from globular proteins in terms of their sequence-structure-function relations. IDPs have lower sequence conservation, different types of active sites and a different distribution of functionally important regions, whic...

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Autori principali: Joanna Lange, Lucjan Wyrwicz, Gert Vriend
Natura: Artigo
Lingua:inglese
Pubblicazione: 2015
Accesso online:https://doi.org/10.1093/bioinformatics/btv663
https://academic.oup.com/bioinformatics/article-pdf/32/6/932/6689201/btv663.pdf
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