A Comparative and Integrative Approach Identifies <i>ATPase Family, AAA Domain Containing 2</i> as a Likely Driver of Cell Proliferation in Lung Adenocarcinoma

A Comparative and Integrative Approach Identifies <i>ATPase Family, AAA Domain Containing 2</i> as a Likely Driver of Cell Proliferation in Lung Adenocarcinoma

To identify genetic changes that could drive cancer pathogenesis in never and ever smokers with lung adenocarcinoma.We analyzed the copy number and gene expression profiles of lung adenocarcinomas in 165 patients and related the alterations to smoking status. Having found differences in the tumor pr...

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Main Authors: Robert Fouret, Julien Laffaire, Paul Hofman, Michèle Beau‐Faller, Julien Mazières, Pierre Validire, Philippe Girard, Sophie Camilleri‐Bröet, F. Vaylet, François Leroy-Ladurie, Jean‐Charles Soria, Pierre Fouret
Format: Artigo
Language:English
Published: 2012
Online Access:https://doi.org/10.1158/1078-0432.ccr-12-0505
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https://doi.org/10.1158/1078-0432.ccr-12-0505

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