Phase I trial of volasertib, a Polo‐like kinase inhibitor, in Japanese patients with acute myeloid leukemia

Phase I trial of volasertib, a Polo‐like kinase inhibitor, in Japanese patients with acute myeloid leukemia

This phase I trial conducted in Japanese patients with acute myeloid leukemia evaluated the safety, maximum tolerated dose and pharmacokinetics of volasertib (BI 6727), a selective Polo-like kinase inhibitor. The primary endpoints were the maximum tolerated dose of volasertib and the incidence of do...

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Bibliografiske detaljer
Main Authors: Yukio Kobayashi, Takahiro Yamauchi, Hitoshi Kiyoi, Toru Sakura, Tomoko Hata, Kiyoshi Ando, Aiko Watabe, Akiko Harada, Tillmann Taube, Yasushi Miyazaki, Tomoki Naoe
Format: Artigo
Sprog:engelsk
Udgivet: 2015
Online adgang:https://doi.org/10.1111/cas.12814
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cas.12814
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https://doi.org/10.1111/cas.12814
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cas.12814

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