Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression
The common age-related neurodegeneration of Parkinson's disease can result from dominant causes like increased dosage of vesicle-associated alpha-synuclein (SNCA) or recessive causes like deficiency of mitophagy factor PINK1. Interactions between these triggers and their convergence onto shared...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | anglès |
| Publicat: |
2014
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| Accés en línia: | https://doi.org/10.1093/hmg/ddu520 https://academic.oup.com/hmg/article-pdf/24/4/1061/14144611/ddu520.pdf |
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