Adeno-Associated Virus Type 2-Mediated Gene Transfer: Correlation of Tyrosine Phosphorylation of the Cellular Single-Stranded D Sequence-Binding Protein with Transgene Expression in Human Cells In Vitro and Murine Tissues In Vivo

Adeno-Associated Virus Type 2-Mediated Gene Transfer: Correlation of Tyrosine Phosphorylation of the Cellular Single-Stranded D Sequence-Binding Protein with Transgene Expression in Human Cells In Vitro and Murine Tissues In Vivo

ABSTRACT Although the adeno-associated virus type 2 (AAV)-based vector system has gained attention as a potentially useful alternative to the more commonly used retroviral and adenoviral vectors for human gene therapy, the single-stranded nature of the viral genome, and consequently the rate-limitin...

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Main Authors: Keyun Qing, Benjawan Khuntirat, Cathryn Mah, Dagmar Marie Kube, Xu-Shan Wang, Selvarangan Ponnazhagan, Shangzhen Zhou, Varavani Dwarki, Mervin C. Yöder, Arun Srivastava
Format: Artigo
Language:English
Published: 1998
Online Access:https://doi.org/10.1128/jvi.72.2.1593-1599.1998
https://jvi.asm.org/content/jvi/72/2/1593.full.pdf
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https://doi.org/10.1128/jvi.72.2.1593-1599.1998
https://jvi.asm.org/content/jvi/72/2/1593.full.pdf

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