Perturbation of Mitosis through Inhibition of Histone Acetyltransferases: The Key to Ochratoxin A Toxicity and Carcinogenicity?

Ochratoxin A (OTA) is one of the most potent rodent renal carcinogens studied to date. Although controversial results regarding OTA genotoxicity have been published, it is now widely accepted that OTA is not a mutagenic, DNA-reactive carcinogen. Instead, increasing evidence from both in vivo and in...

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Huvudupphovsmän: Kristin Bernadette Czakai, Katja Müller, Pasquale Mosesso, Gaetano Pepe, Markus Schulze, Antje Gohla, Debasis Patnaik, W. Dekant, Jonathan M.G. Higgins, Angela Mally
Materialtyp: Artigo
Språk:engelska
Publicerad: 2011
Länkar:https://doi.org/10.1093/toxsci/kfr110
https://academic.oup.com/toxsci/article-pdf/122/2/317/16682930/kfr110.pdf
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