ATM specifically mediates repair of double-strand breaks with blocked DNA ends
Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative syndromes linked to deficiencies in the DNA-damage response. The role of ATM as a key regulator of signalling following DNA double-strand breaks (DSBs) has been dissected in...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2014
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| Online Access: | https://doi.org/10.1038/ncomms4347 https://www.nature.com/articles/ncomms4347.pdf |
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