Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells

Induced pluripotent stem cells (iPSCs) have been derived at low frequencies from different cell types through ectopic expression of the transcription factors Oct4 and Sox2, combined with either Klf4 and c-Myc or Lin28 and Nanog. In order to generate iPSCs more effectively, it will be crucial to iden...

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Principais autores: Jochen Utikal, Nimet Maherali, Warakorn Kulalert, Konrad Hochedlinger
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Acesso em linha:https://doi.org/10.1242/jcs.054783
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