A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

Complex focal chromosomal rearrangements in cancer genomes, also called “firestorms”, can be scored from DNA copy number data. The complex arm‐wise aberration index (CAAI) is a score that captures DNA copy number alterations that appear as focal complex events in tumors, and has potential prognostic...

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Hlavní autoři: Hans Kristian Moen Vollan, Oscar M. Rueda, Suet‐Feung Chin, Christina Curtis, Gulisa Turashvili, Sohrab P. Shah, Ole Christian Lingjærde, Yinyin Yuan, Charlotte K.Y. Ng, Mark Dunning, Ed Dicks, Elena Provenzano, Stephen‐John Sammut, Steven McKinney, Ian O. Ellis, Sarah E. Pinder, Arnie Purushotham, Leigh C. Murphy, Vessela N. Kristensen, James D. Brenton, Paul D.P. Pharoah, Anne‐Lise Børresen‐Dale, Samuel Aparício, Carlos Caldas
Médium: Artigo
Jazyk:angličtina
Vydáno: 2014
On-line přístup:https://doi.org/10.1016/j.molonc.2014.07.019
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