Differential Regulation of P27Kip1 Expression by Mitogenic and Hypertrophic Factors
Platelet-derived growth factor-BB (PDGF-BB) acts as a full mitogen for cultured aortic smooth muscle cells (SMC), promoting DNA synthesis and cell proliferation. In contrast, angiotensin II (Ang II) induces cellular hypertrophy as a result of increased protein synthesis, but is unable to drive cells...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2000
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| 在線閱讀: | https://doi.org/10.1083/jcb.148.3.543 https://rupress.org/jcb/article-pdf/148/3/543/1290298/9908096.pdf |
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