Differential Regulation of P27Kip1 Expression by Mitogenic and Hypertrophic Factors
Platelet-derived growth factor-BB (PDGF-BB) acts as a full mitogen for cultured aortic smooth muscle cells (SMC), promoting DNA synthesis and cell proliferation. In contrast, angiotensin II (Ang II) induces cellular hypertrophy as a result of increased protein synthesis, but is unable to drive cells...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2000
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| On-line přístup: | https://doi.org/10.1083/jcb.148.3.543 https://rupress.org/jcb/article-pdf/148/3/543/1290298/9908096.pdf |
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