Regulation of the Anaphase-promoting Complex by the Dual Specificity Phosphatase Human Cdc14a
Two forms of the anaphase-promoting complex (APC) mediate the degradation of critical cell cycle regulators. APCCdc20 promotes sister-chromatid separation by ubiquitinating securin, whereas APCCdh1 ubiquitinates mitotic cyclins, allowing the exit from mitosis. Here we show that phosphorylation of hu...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | engelsk |
| Udgivet: |
2001
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| Online adgang: | https://doi.org/10.1074/jbc.m108126200 http://www.jbc.org/article/S0021925819403402/pdf |
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