Regulation of the Anaphase-promoting Complex by the Dual Specificity Phosphatase Human Cdc14a

Regulation of the Anaphase-promoting Complex by the Dual Specificity Phosphatase Human Cdc14a

Two forms of the anaphase-promoting complex (APC) mediate the degradation of critical cell cycle regulators. APCCdc20 promotes sister-chromatid separation by ubiquitinating securin, whereas APCCdh1 ubiquitinates mitotic cyclins, allowing the exit from mitosis. Here we show that phosphorylation of hu...

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书目详细资料
Main Authors:	Joshua N. Bembenek, Hongtao Yu
格式:	Artigo
语言:	英语
出版:	2001
在线阅读:	https://doi.org/10.1074/jbc.m108126200 http://www.jbc.org/article/S0021925819403402/pdf
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