Analysis of Uromodulin Polymerization Provides New Insights into the Mechanisms Regulating ZP Domain-mediated Protein Assembly

Analysis of Uromodulin Polymerization Provides New Insights into the Mechanisms Regulating ZP Domain-mediated Protein Assembly

Uromodulin is the most abundant protein secreted in urine, in which it is found as a high-molecular-weight polymer. Polymerization occurs via its zona pellucida (ZP) domain, a conserved module shared by many extracellular eukaryotic proteins that are able to assemble into matrices. In this work, we...

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Bibliografiske detaljer
Main Authors:	Céline Schaeffer, S Santambrogio, Simone Perucca, Giorgio Casari, Luca Rampoldi
Format:	Artigo
Sprog:	engelsk
Udgivet:	2008
Online adgang:	https://doi.org/10.1091/mbc.e08-08-0876
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Lignende værker

Analysis of Uromodulin Polymerization Provides New Insights into the Mechanisms Regulating ZP Domain-mediated Protein Assembly
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