Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation
VE-cadherin-mediated cell-cell junction weakening increases paracellular permeability in response to both angiogenic and inflammatory stimuli. Although Semaphorin 3A has emerged as one of the few known anti-angiogenic factors to exhibit pro-permeability activity, little is known about how it trigger...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
2012
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Online Access: | https://doi.org/10.1242/jcs.108282 |
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