SOCS1, SOCS3, and PIAS1 Promote Myogenic Differentiation by Inhibiting the Leukemia Inhibitory Factor-Induced JAK1/STAT1/STAT3 Pathway
We recently showed that a leukemia inhibitory factor (LIF)-engaged signaling pathway consisting of JAK1, STAT1, and STAT3 plays dual roles in myogenic differentiation: while it participates in myoblast proliferation, it also actively represses differentiation. Downregulation of this pathway is requi...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2009
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| On-line přístup: | https://doi.org/10.1128/mcb.00267-09 |
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