Dynamics of site juxtaposition in supercoiled DNA

Juxtaposition kinetics between specific sites in supercoiled DNA is investigated at close to physiological ionic conditions by Brownian dynamics simulations. At such conditions, supercoiled DNA is interwound, and the probability of spatial site juxtaposition is much higher than in relaxed DNA. We fi...

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Main Authors: Jing Huang, Tamar Schlick, Alexander Vologodskii
格式: Artigo
語言:英语
出版: 2001
在線閱讀:https://doi.org/10.1073/pnas.98.3.968
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