In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I

OBJECTIVE The activation of AMP-activated protein kinase (AMPK) has been reported to improve endothelial function. However, the targets of AMPK in endothelial cells remain poorly defined. The aim of this study was to test whether AMPK suppresses the degradation of GTP-cyclohydrolase (GTPCH I), a key...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Shuangxi Wang, Jian Xu, Ping Song, Benoı̂t Viollet, Ming‐Hui Zou
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2009
Rochtain ar líne:https://doi.org/10.2337/db09-0267
https://diabetesjournals.org/diabetes/article-pdf/58/8/1893/663366/zdb00809001893.pdf
Clibeanna: Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!