Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27<sup>Kip1</sup>

During development of the central nervous system, oligodendrocyte progenitor cells (O-2A) undergo an orderly pattern of cell proliferation and differentiation, culminating in the ability of oligodendrocytes to myelinate axons. Here we report that p27(Kip1), a cyclin-dependent kinase inhibitor, is an...

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Main Authors: Patrizia Casaccia‐Bonnefil, Ravi Tikoo, Hiroaki Kiyokawa, Victor L. Friedrich, Moses V. Chao, Andrew Koff
Format: Artigo
Jezik:angleščina
Izdano: 1997
Online dostop:https://doi.org/10.1101/gad.11.18.2335
http://genesdev.cshlp.org/content/11/18/2335.full.pdf
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