Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks
The DNA damage checkpoint plays a crucial role in maintaining functional DNA replication forks when cells are exposed to genotoxic agents. In budding yeast, the protein kinases Mec1 (ATR) and Rad53 (Chk2) are especially important in this process. How these kinases act to stabilize DNA replication fo...
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| Main Authors: | , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2008
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| 在线阅读: | https://doi.org/10.1101/gad.477208 http://genesdev.cshlp.org/content/22/13/1816.full.pdf |
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