Isoaspartate-Glycine-Arginine: A New Tumor Vasculature–Targeting Motif
Abstract Asparagine deamidation in peptides or in fibronectin fragments containing the asparagine-glycine-arginine sequence generates isoaspartate-glycine-arginine (isoDGR), a new αvβ3 integrin-binding motif. Because αvβ3 is expressed in angiogenic vessels, we hypothesized that isoDGR-containing pep...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2008
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| Online Access: | https://doi.org/10.1158/0008-5472.can-08-1272 https://aacrjournals.org/cancerres/article-pdf/68/17/7073/2593548/7073.pdf |
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