Molecular Mechanism of SAHA on Regulation of Autophagic Cell Death in Tamoxifen-Resistant MCF-7 Breast Cancer Cells

Objective: Tamoxifen is currently used for the treatment of estrogen receptor-positive breast cancer patients, but acquired resistance to tamoxifen is a critical problem in breast cancer therapy.Suberoylanilide hydroxamic acid (SAHA) is a prototype of the newly developed HDAC inhibitor.The aim of th...

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Bibliographic Details
Main Authors: Young Ju Lee, A Jin Won, Jaewon Lee, Jee H. Jung, Sungpil Yoon, Byung Mu Lee, Hyung Sik Kim
Format: Artigo
Language:English
Published: 2012
Online Access:https://doi.org/10.7150/ijms.5011
https://www.medsci.org/v09p0881.pdf
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