Regulation of dendritic cell activation by microRNA let-7c and BLIMP1

Mice with a DC-specific deletion of the transcriptional repressor B lymphocyte–induced maturation protein-1 (Blimp1) exhibit a lupus-like phenotype, secondary to enhanced DC production of IL-6. Here we explored further phenotypic changes in Blimp1-deficient DCs, the molecular mechanism underlying th...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Sun Jung Kim, Peter K. Gregersen, Betty Diamond
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2013
Rochtain ar líne:https://doi.org/10.1172/jci64712
http://www.jci.org/articles/view/64712/files/pdf
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