Regulation of dendritic cell activation by microRNA let-7c and BLIMP1
Mice with a DC-specific deletion of the transcriptional repressor B lymphocyte–induced maturation protein-1 (Blimp1) exhibit a lupus-like phenotype, secondary to enhanced DC production of IL-6. Here we explored further phenotypic changes in Blimp1-deficient DCs, the molecular mechanism underlying th...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2013
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| Online-Zugang: | https://doi.org/10.1172/jci64712 http://www.jci.org/articles/view/64712/files/pdf |
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