Quantitative Imaging of Single Live Cells Reveals Spatiotemporal Dynamics of Multistep Signaling Events of Chemoattractant Gradient Sensing in<i>Dictyostelium</i>
Activation of G-protein-coupled chemoattractant receptors triggers dissociation of Galpha and Gbetagamma subunits. These subunits induce intracellular responses that can be highly polarized when a cell experiences a gradient of chemoattractant. Exactly how a cell achieves this amplified signal polar...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | engelsk |
| Udgivet: |
2004
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| Online adgang: | https://doi.org/10.1091/mbc.e04-07-0544 |
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