Impaired Recycling of Apolipoprotein E4 Is Associated with Intracellular Cholesterol Accumulation
After internalization of triglyceride-rich lipoproteins (TRL) in hepatoma cells, TRL particles are immediately disintegrated in the early endosomal compartment. This involves the targeting of lipids and apoprotein B along the degradative pathway and the recycling of TRL-derived apoE through recyclin...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2004
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| 在线阅读: | https://doi.org/10.1074/jbc.m409324200 http://www.jbc.org/article/S0021925818663112/pdf |
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