RhoA activation during polarization and cytokinesis of the early <i>Caenorhabditis elegans</i> embryo is differentially dependent on NOP-1 and CYK-4

The GTPase RhoA is a central regulator of cellular contractility in a wide variety of biological processes. During these events, RhoA is activated by guanine nucleotide exchange factors (GEFs). These molecules are highly regulated to ensure that RhoA activation occurs at the proper time and place. D...

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Bibliographic Details
Main Authors: Yu Chung Tse, Michael E. Werner, Katrina M Longhini, Jean‐Claude Labbé, Bob Goldstein, Michael Glotzer
Format: Artigo
Language:English
Published: 2012
Online Access:https://doi.org/10.1091/mbc.e12-04-0268
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