The Involvement of the Intestinal Microflora in theExpansion of CD4<sup>+</sup> T Cells with a‐Naive Phenotype inthe Periphery

It is well known that immune reactivity declines with age. Recently, we demonstrated that the age‐related decrease in IL‐2 production by CD4 + T cells was accompanied by an increased production of IL‐4 and interferon‐ γ ,(IFN‐ γ ). This age‐related shift in the profile of lymphokine production was r...

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Autori principali: Ruud Dobber, Anita Hertogh‐Huijbregts, Jan Rozing, Kim Bottomly, Lex Nagelkerken
Natura: Artigo
Lingua:inglese
Pubblicazione: 1992
Accesso online:https://doi.org/10.1155/1992/57057
https://downloads.hindawi.com/journals/jir/1992/057057.pdf
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