Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study

Breast cancer brain metastases (BCBM) are challenging complications that respond poorly to systemic therapy. The role of the blood–tumor barrier in limiting BCBM drug delivery and efficacy has been debated. Herein, we determined tissue and serum levels of capecitabine, its prodrug metabolites, and l...

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Main Authors: Aki Morikawa, David M. Peereboom, Helen R. Thorsheim, Ramakrishna Samala, Rajiv Balyan, Conleth G. Murphy, Paul R. Lockman, Ahkeem James Simmons, Robert J. Weil, Viviane Tabar, Patricia S. Steeg, Quentin R. Smith, Andrew D. Seidman
Format: Artigo
Language:English
Published: 2014
Online Access:https://doi.org/10.1093/neuonc/nou141
https://academic.oup.com/neuro-oncology/article-pdf/17/2/289/16859179/nou141.pdf
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