Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient survival in cancer, we aimed at investigating a potential prognostic...

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Главные авторы: Jürgen Veeck, Peter J. Wild, Thomas J. Fuchs, Peter J. Schüffler, Arndt Hartmann, Ruth Knüchel, Edgar Dahl
Формат: Artigo
Язык:английский
Опубликовано: 2009
Online-ссылка:https://doi.org/10.1186/1471-2407-9-217
https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-9-217
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