Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient survival in cancer, we aimed at investigating a potential prognostic...

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Autori principali: Jürgen Veeck, Peter J. Wild, Thomas J. Fuchs, Peter J. Schüffler, Arndt Hartmann, Ruth Knüchel, Edgar Dahl
Natura: Artigo
Lingua:inglese
Pubblicazione: 2009
Accesso online:https://doi.org/10.1186/1471-2407-9-217
https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-9-217
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