Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient survival in cancer, we aimed at investigating a potential prognostic...

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Bibliographic Details
Main Authors: Jürgen Veeck, Peter J. Wild, Thomas J. Fuchs, Peter J. Schüffler, Arndt Hartmann, Ruth Knüchel, Edgar Dahl
Format: Artigo
Language:English
Published: 2009
Online Access:https://doi.org/10.1186/1471-2407-9-217
https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-9-217
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