Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient survival in cancer, we aimed at investigating a potential prognostic...

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Autors principals: Jürgen Veeck, Peter J. Wild, Thomas J. Fuchs, Peter J. Schüffler, Arndt Hartmann, Ruth Knüchel, Edgar Dahl
Format: Artigo
Idioma:anglès
Publicat: 2009
Accés en línia:https://doi.org/10.1186/1471-2407-9-217
https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-9-217
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