Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis
Galectin-1 (Gal-1), a carbohydrate-binding protein whose secretion is enhanced by hypoxia, promotes tumor aggressiveness by promoting angiogenesis and T-cell apoptosis. However, the importance of tumor versus host Gal-1 in tumor progression is undefined. Here we offer evidence that implicates tumor...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2011
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| 在線閱讀: | https://doi.org/10.1158/0008-5472.can-10-4157 https://aacrjournals.org/cancerres/article-pdf/71/13/4423/2653827/4423.pdf |
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